New outbreaks (1)
Diagnostic test results
Tuesday, December 23, 2014
FDA PART 589 -- SUBSTANCES PROHIBITED FROM USE IN ANIMAL FOOD OR FEED VIOLATIONS OFFICIAL ACTION INDICATED OAI UPDATE DECEMBER 2014 BSE TSE PRION
Wednesday, December 24, 2014
National Scrapie Eradication Program November 2014 Monthly Report Fiscal Year 2015
Tuesday, December 16, 2014
Evidence for zoonotic potential of ovine scrapie prions
Scrapie from sheep could infect humans with 'mad cow disease', study finds
*** HUMAN MAD COW DISEASE nvCJD TEXAS CASE NOT LINKED TO EUROPEAN TRAVEL CDC ***
Sunday, November 23, 2014
*** Confirmed Variant Creutzfeldt-Jakob Disease (variant CJD) Case in Texas in June 2014 confirmed as USA case NOT European
the patient had resided in Kuwait, Russia and Lebanon. The completed investigation did not support the patient's having had extended travel to European countries, including the United Kingdom, or travel to Saudi Arabia. The specific overseas country where this patient’s infection occurred is less clear largely because the investigation did not definitely link him to a country where other known vCJD cases likely had been infected.
Sunday, December 14, 2014
ALERT new variant Creutzfeldt Jakob Disease nvCJD or vCJD, sporadic CJD strains, TSE prion aka Mad Cow Disease United States of America Update December 14, 2014 Report
Saturday, December 13, 2014
Terry S. Singeltary Sr. Publications TSE prion disease
for my files...tss
Diagnosis and Reporting of Creutzfeldt-Jakob Disease
Singeltary, Sr et al. JAMA.2001; 285: 733-734. Vol. 285 No. 6, February 14, 2001 JAMA
Sent: Friday, June 20, 2014 11:10 AM
Subject: ROU 20-06-14 OIE Alert - Alerta - Alerte - Bovine spongiform encephalopathy - Encéphalopathie spongiforme bovine - Encefalopatía espongiforme bovina
English PDF reports Français Rapports PDF Español informes PDF
Bovine spongiform encephalopathy ,Romania Information received on 20/06/2014 from Dr Cristian Duicu, Director General, National Veterinary and Food Safety Authority for General Sanitary Veterinary Department, Ministry of Agriculture and Food, Bucharest , Romania
Summary Report type Immediate notification Date of start of the event 06/05/2014 Date of pre-confirmation of the event 09/06/2014 Report date 20/06/2014 Date submitted to OIE 20/06/2014 Reason for notification First occurrence of a listed disease Manifestation of disease Sub-clinical infection Causal agent Prion (atypical BSE L-type) Nature of diagnosis Laboratory (advanced) This event pertains to the whole country
New outbreaks Summary of outbreaks Total outbreaks: 1 Outbreak Location CLUJ ( Deusu, Deusu, Chinteni ) Total animals affected Species Susceptible Cases Deaths Destroyed Slaughtered Cattle 1 0 0 0 Outbreak statistics Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost* Cattle ** ** 0.00% **
* Removed from the susceptible population through death, destruction and/or slaughter; ** Not calculated because of missing information;
Epidemiology Source of the outbreak(s) or origin of infection Unknown or inconclusive Epidemiological comments The investigation is ongoing.
Control measures Measures applied Movement control inside the country No vaccination No treatment of affected animals Measures to be applied No other measures
Diagnostic test results Laboratory name and type Institute for Diagnosis and Animal Health ( National laboratory ) Tests and results Species Test Test date Result Cattle western blot 09/06/2014 Positive Laboratory name and type Animal Health and Veterinary Laboratories Agency (AHVLA), Weybridge, United Kingdom ( OIEs Reference Laboratory ) Tests and results Species Test Test date Result Cattle immunohistochemical test 12/06/2014 Positive Cattle western blot 12/06/2014 Positive
Future Reporting The event is continuing. Weekly follow-up reports will be submitted.
Encéphalopathie spongiforme bovine ,Roumanie Information reçue le 20/06/2014 de Dr Cristian Duicu, Director General, National Veterinary and Food Safety Authority for General Sanitary Veterinary Department, Ministry of Agriculture and Food, Bucharest , Roumanie
Résumé Type de rapport Notification immédiate Date de début de lévénement 06/05/2014 Date de pré-confirmation de l´événement 09/06/2014 Date du rapport 20/06/2014 Date d'envoi à l'OIE 20/06/2014 Raison de notification Apparition pour la première fois dune maladie appartenant à la liste de l'OIE Manifestation de la maladie Infection sub-clinique Agent causal Prion (ESB atypique type L) Nature du diagnostic Tests approfondis en laboratoire (i.e. virologie, microscopie électronique, biologie moléculaire, immunologie) Cet événement se rapporte à tout le pays
Nouveaux foyers Récapitulatif des foyers Nombre total de foyers : 1 Localisation du foyer CLUJ ( Deusu, Deusu, Chinteni ) Nombre total d'animaux atteints Espèce(s) Sensibles Cas Morts Détruits Abattus Bovins 1 0 0 0 Statistiques sur le foyer Espèce(s) Taux de morbidité apparent Taux de mortalité apparent Taux de fatalité apparent Proportion d'animaux sensibles perdus* Bovins ** ** 0.00% **
* Soustraits de la population sensible suite à la mort, à l´abattage et/ou à la destruction; ** Non calculé par manque de données;
Epidémiologie Source du/des foyer(s) ou origine de l´infection Inconnue ou incertaine Autres renseignements épidémiologiques / Commentaires L'enquête est en cours.
Mesures de lutte Mesure de lutte appliquées Restriction des déplacements à l'intérieur du pays Pas de vaccination Aucun traitement des animaux atteints Mesures à appliquer Aucune autre mesure
Résultats des tests de diagnostics Nom du laboratoire et type Agence des Laboratoires vétérinaires et santé animale (AHVLA), Weybridge (Royaume-Uni) ( Laboratoire de référence de lOIE ) Tests et résultats Espèce(s) Test Date du test Résultat Bovins examen immunohistochimique 12/06/2014 Positif Bovins western blot 12/06/2014 Positif Nom du laboratoire et type Institut de diagnostic et de santé animale ( Laboratoire national ) Tests et résultats Espèce(s) Test Date du test Résultat Bovins western blot 09/06/2014 Positif
Rapports futurs Cet événement se poursuit. Des rapports de suivi hebdomadaires devront être envoyés.
Encefalopatía espongiforme bovina ,Rumania Información recibida el 20/06/2014 desde Dr Cristian Duicu, Director General, National Veterinary and Food Safety Authority for General Sanitary Veterinary Department, Ministry of Agriculture and Food, Bucharest , Rumania
Resumen Tipo de informe Notificación inmediata Fecha del inicio del evento 06/05/2014 Fecha de pre-confirmación del evento 09/06/2014 Fecha del informe 20/06/2014 Fecha de envio del informe a la OIE 20/06/2014 Motivo de la notificación Aparición por primera vez de una enfermedad de la Lista de la OIE Manifestación de la enfermedad Infección sub-clínica Agente causal Prion (EEB atípica tipo L) Naturaleza del diagnóstico Pruebas de diagnóstico de laboratorio avanzadas (ej. virología, microscopía electrónica, biología molecular e inmunología) Este evento concierne todo el país
Nuevos focos Resumen de los focos Número total de focos: 1 Localización del foco CLUJ ( Deusu, Deusu, Chinteni ) Número total de animales afectados Especies Susceptibles Casos Muertos Destruidos Sacrificados Bovinos 1 0 0 0 Estadística del foco Especies Tasa de morbilidad aparente Tasa de mortalidad aparente Tasa de fatalidad aparente Proporción de animales susceptibles perdidos* Bovinos ** ** 0.00% **
* Descontados de la población susceptible a raíz de su muerte, destrucción o sacrificio; ** No calculado por falta de datos;
Epidemiología Fuente del o de los focos u origen de la infección Desconocida o no concluyente Otros detalles epidemiológicos / comentarios Se está investigando.
Medidas de Control Medidas implementadas Restricción de los movimientos en el interior del país Vacunación: no Ningún tratamiento de los animales afectados Medidas para implementar Ninguna otra medida
Resultados de las pruebas diagnósticas Nombre y tipo de laboratorio Agencia de laboratorios veterinarios y sanidad animal (AHVLA), Weybridge (Reino Unido) ( Laboratorio de referencia de la OIE ) Pruebas y resultados Especies Prueba Fecha de la prueba Resultados Bovinos examen inmunohistoquímico 12/06/2014 Positivo Bovinos western blot 12/06/2014 Positivo Nombre y tipo de laboratorio Instituto de diagnóstico y sanidad animal ( Laboratorio nacional ) Pruebas y resultados Especies Prueba Fecha de la prueba Resultados Bovinos western blot 09/06/2014 Positivo
Informes futuros El episodio continúa. Informes de seguimiento semanales serán enviados
Brussels, 16 May 2001
BSE: Scientists publish risk assessments for Costa Rica, Kenya, Slovenia and Romania
The Scientific Steering Committee (SSC) advising the European Commission on BSE related issues has today published its opinion on the Geographical Risk of Bovine Spongiform Encephalopathy (GBR) in Costa Rica, Kenya, Slovenia and Romania. The evaluation of the geographical risk of presence of BSE focuses on the risk for animals to incubate the disease. The Committee concludes that is highly unlikely that cattle infected with the BSE agent are present in domestic herds of Costa Rica (GBR level I). They found that this is unlikely but not excluded in the herds of Kenya and Slovenia (GBR level II) and that it is likely that BSE is present in the cattle herds of Romania (GBR level III) although this is not yet confirmed. Slovenia is the first accession country that is classified as GBR level II. All other accession countries evaluated so far have been classified at level III of Geographical BSE Risk. Similarly, all EU Member States are classified at level III except for Sweden, Finland and Austria (level II) and United Kingdom and Portugal (level IV).
The Committee found that Slovenia has since 1992 imported 2.400 live cattle notably from Germany, and imported small amounts of MBM. The Slovenian authorities have been able to trace most of these cattle imports and to demonstrate that many of them are still alive. They also showed that reasonably effective controls on the rendering of MBM were in place at least as of 1996, and probably also before that date. In addition, a first feed ban to ruminants was introduced in 1996. It is therefore regarded unlikely but not excluded that the BSE agent could have been recycled, but not amplified, in Slovenia between 1992 and January 2001, when a complete feed ban was put in place. Romania has imported higher numbers of live cattle (about 22,000 tons) and meat-and-bone-meal (about 10,000 tons) from EU countries where the presence of BSE has since been confirmed. Although risk management measures were taken as of 1996, their effective enforcement has not been demonstrated. Therefore it is regarded likely that Romanian cattle herds were exposed to potentially BSE contaminated feed and subsequently infected.
Kenya has received meat and bone meal exports notably between 1987-1990 from the UK and since 1994 from Belgium, Denmark and the Netherlands. The data made available to the SSC do not exclude that some of this MBM has reached domestic cattle. The conclusion of the assessment for Costa Rica is based on data demonstrating that BSE infectivity is highly unlikely to have reached the country and hence the domestic cattle population. Only minor quantities of potentially infected live cattle (35 from Spain) or potentially contaminated meat-and-bone meal (5 tonnes) were imported into the country.
The SSC recommends that BSE related aspects are included in the programme of future inspection missions of the Food and Veterinary Office, as far as feasible, to obtain confirmation of the information received from the national authorities in the countries concerned. For the time being, the scientists underline, their assessment has to be based on the information provided by the assessed countries. As far as possible all data have been evaluated and verified in close co-operation with the countries concerned, and checked against other sources in an open and transparent manner. Data on imports provided by the countries under evaluation have for example been compared with export data as recorded by EUROSTAT, the EU Statistical Office, and with export data provided by the UK authorities.
The evaluation of the GBR in these third countries was made on the basis of the same method and assessment process as described by the SSC in its July 2000 opinion on the GBR( 1 ). In the July-opinion the scientists already assessed the GBR risk in all EU Member States except Greece, and a first series of third countries( 2 ). An assessment for Uruguay was published in January; assessments for Botswana, Lithuania, Namibia, Nicaragua, and Swaziland in February, and for Albania, Brazil, Colombia, Republic of Cyprus, Czech Republic, Estonia, Hungary, India, Mauritius, Pakistan, Poland, Singapore and Slovakia in April this year.
The full text of the opinions is available at:
Released on 29/05/2001
Updated Overview of third countries according to Geographical BSE risk classification
Category I: Highly unlikely to present a BSE risk
Argentina Australia Botswana Brazil Chile Costa Rica Namibia Nicaragua Norway New Zealand Paraguay Singapore Swaziland Uruguay
Category II: Unlikely, but a BSE risk cannot be excluded
Canada Colombia India Kenya Mauritius Pakistan Slovenia USA
Category III: likely to present a BSE risk, even if not confirmed, or presenting a low level of confirmed BSE risk
Albania Cyprus Czech Republic Estonia Hungary Lithuania Poland Romania Slovak Republic Switzerland
Category IV: BSE risk confirmed at a high level
1 see IP of August1, 2000 at :
2 Argentina, Australia, Canada, Chile, Norway, New Zealand, Paraguay, Switzerland, USA
2004 BSE GBR
Opinion of the Scientific Steering Committee on the GEOGRAPHICAL RISK OF BOVINE SPONGIFORM ENCEPHALOPATHY (GBR) in Romania Adopted on 11/05/2001
FINAL REPORT OF AN AUDIT CARRIED OUT IN ROMANIA FROM 07 TO 18 FEBRUARY 2011 IN ORDER TO EVALUATE MEASURES CONCERNING BOVINE SPONGIFORM ENCEPHALOPATHY (BSE)
Executive Summary This report describes the outcome of an audit carried out by the Food and Veterinary Office (FVO) in Romania, from 7 to 18 February 2011.
The objective of the audit was to evaluate the implementation of requirements concerning Bovine Spongiform Encephalopathy (BSE), as laid down in Regulation (EC) No 999/2001.
In terms of scope, the audit concentrated on BSE epidemio-surveillance in bovines, measures taken after suspicion/confirmation of BSE, removal and handling of specified risk material (SRM) from bovines, and the prohibition of feeding products of animal origin to farmed animals and exceptions applicable to this ban. The evaluation included measures taken in response to the recommendations made in a previous FVO audit regarding the afore-mentioned issues.
Overall, the report concludes that very limited progress has been made in order to address the recommendations of the previous FVO audit. In particular, BSE active epidemio-surveillance and compliance with SRM rules are significantly affected by the lack of arrangements for the collection of brain samples and SRM at backyard farms, where the majority of the bovine population is kept. There are also weaknesses concerning feed-ban controls.
The report makes a number of recommendations addressed to the Romanian competent authorities, aimed at rectifying the shortcomings identified and further enhancing the implementing and control measures in place.
Friday, January 17, 2014
Annual report of the Scientific Network on BSE-TSE EFSA, Question No EFSA-Q-2013-01004, approved on 11 December 2013 TECHNICAL REPORT